Folinic Acid: Why Folate Type Matters | MTHFR

You may have heard of MTHFR, which stands for Methylenetetrahydrofolate Reductase. This is an enzyme in the body that is crucial in making methylation happen which has so many incredible roles in our bodies. 

Rise + Shine our start morning formulation has specifically been chosen to contain activated form of folate, folinic acid opposed to your most commonly found synthetic folic acid. 

Why does it matter?

A recent podcast between Gary Brecka and Joe Rogan brought huge awareness to the importance of methylation and methylated supplements for health. It is estimated that between 30-60% of people have an MTHFR mutation and associated issues with methylation as a result of this. In simple terms with such a large portion of people having a mutation in this gene it means that the type of folate you take matters.

Risk Associated with the MTHFR mutation and resulting low enzyme activity?

- Heart Health: Elevated homocysteine levels, a risk factor for cardiovascular diseases as a result of poor methylation activity and subsequent low folate/b12 levels. 

- Fatigue: A folate deficiency can cause fatigue as it promotes more energy.

- Fertility Concerns: Pregnant women, especially those with MTHFR mutations, will benefit from methylated forms of folic acid such as folinic acid in Rise+Shine to ensure adequate absorption. However, it's essential to consult with a healthcare provider to determine the right supplementation during pregnancy.

- Mental Health: Studies show that people with the MTHFR gene variant are more likely to have mood disorders such as depression, anxiety, schizophrenia, and bipolar disorder. 

Supporting nutritional status with activated forms of nutrients can support a reduction in the above risk factors beautifully, however does not replace the need for practitioner support if you are experiencing any of the above.